人们已知胸腺是T淋巴细胞发生的场所,但对胸腺内细胞谱系相互之间的关系却知之甚少.根据抗T细胞分化抗原Lyt2和L3T4单克隆抗体染色,至少能将小鼠胸腺细胞分为4个亚群.如同外周T细胞一样,髓质的免疫活性胸腺细胞或者表达Lyt2(细胞毒性表现型),或者表达L3T4 It is known that the thymus is a site where T lymphocytes occur but little is known about the relationship between the cell lineages in the thymus.According to the staining of the anti-T cell differentiation antigens Lyt2 and L3T4 monoclonal antibodies, at least the mouse thymocytes 4 subpopulations.As with peripheral T cells, medulla immunoreactive thymocytes either express Lyt2 (cytotoxic phenotype) or express L3T4