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目的观察尼莫地平治疗高血压性脑出血的疗效及安全性。方法 158例高血压性脑出血患者随机分为观察组和对照组,各79例。对照组接受常规治疗,观察组接受尼莫地平治疗,静脉滴注尼莫地平注射液20 mg/d,滴注时间为2周,患者病情稳定之后,口服尼莫地平进行治疗,口服3次/d,服用40 mg/次,治疗1个月后比较两组患者临床治疗效果。结果观察组临床治疗总有效率明显高于对照组,其神经功能缺损评分明显低于对照组,两组比较差异均有统计学意义(P<0.05)。结论尼莫地平能有效提高高血压性脑出血患者的临床治疗效果,保护其神经功能,有效改善患者预后情况。
Objective To observe the efficacy and safety of nimodipine in the treatment of hypertensive intracerebral hemorrhage. Methods 158 cases of hypertensive intracerebral hemorrhage were randomly divided into observation group and control group, 79 cases each. The control group received routine treatment, the observation group received nimodipine treatment, intravenous injection of nimodipine 20 mg / d, infusion time of 2 weeks, the patient was stable, oral nimodipine for treatment, oral 3 times / d, taking 40 mg / time, after 1 month of treatment compared the clinical efficacy of two groups of patients. Results The total effective rate of clinical treatment in observation group was significantly higher than that in control group, and the score of neurological deficit in observation group was significantly lower than that in control group. There was significant difference between the two groups (P <0.05). Conclusion Nimodipine can effectively improve the clinical effect of patients with hypertensive intracerebral hemorrhage, protect their neurological function and effectively improve the prognosis of patients.