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目的观察30 d-6°头低位卧床实验后志愿者腰椎高度、腰椎间隙中矢状位面积、腰椎前凸角度以及椎旁肌肉横切面积的变化。方法 14名健康男性参加30 d卧床模拟失重实验。于卧床前1天、卧床第30天分别进行腰椎核磁检测,同时测量人体腰椎高度、腰椎间隙中矢状位面积、腰椎前凸角度以及椎旁肌肉横切面积。结果 30 d卧床实验后志愿者腰椎高度增加(P<0.01)、腰椎间隙中矢状位面积增大(P<0.01),椎旁肌肉横切面积减少(P<0.01),而腰椎前凸角度变化不明显。结论 30 d-6°头低位卧床模拟失重对人体腰椎稳定性和功能有影响,从而导致人体腰椎的生物力学变化。
Objective To observe the changes of lumbar height, lumbar intervertebral sagittal area, lumbar lordosis and paravertebral muscle cross-sectional area of 30 d-6 ° head-down ambulation in volunteers. Methods Fourteen healthy male volunteers participated in simulated weightlessness test for 30 days in bed. At 1 day before bedtime and 30 days after bed rest, the lumbar MRI was performed. The lumbar spine height, lumbar intervertebral sagittal area, lumbar lordosis and paravertebral muscle cross-sectional area were also measured. Results After 30 days of bed rest, the height of lumbar spine increased (P <0.01), the sagittal area of lumbar intervertebral space increased (P <0.01) and the paravertebral muscle cross sectional area decreased (P <0.01), while the lumbar lordosis angle Not obvious. Conclusions The 30d-6 ° head-on-bed simulated weightlessness has an impact on the stability and function of the lumbar spine, which leads to the biomechanical changes of the human lumbar spine.