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目的探讨单眼中心性浆液性脉络膜视网膜病变(CSC)患者的患眼与健眼黄斑中心凹下脉络膜厚度是否有差异。方法选取2016年1月~2017年1月期间经荧光素钠眼底血管造影(FFA)、脉络膜深层成像光学相干断层扫描(EDI-OCT)检查,确诊为单眼CSC的50例患者作为研究对象,应用EDI-OCT仪器自带的测量软件,在黄斑中心凹下从视网膜色素上皮(RPE)高反射线的外部至可见的巩膜内表面测定患眼与健眼的脉络膜厚度。结果 50例单眼CSC患者的患眼与健眼黄斑中心凹下脉络膜厚度为(443.36±73.54)μm,(392.67±87.82)μm,两者之间差异具有统计学意义(P<0.05)。结论 CSC患者的患眼黄斑中心凹下脉络膜厚度明显比健眼增高,对CSC的发病机制有了更深的了解,为其在临床上的诊疗提供帮助。同时,EDI-OCT检查技术是观察脉络膜厚度的重要方法。
Objective To investigate whether there is a difference in the choroid thickness of patients with monocular central serous chorioretinopathy (CSC). Methods Fifty patients diagnosed as monocular CSC from January 2016 to January 2017 with fluorescein sodium fundus angiography (FFA) and choroidal deep imaging optical coherence tomography (EDI-OCT) were selected as research objects. The measurement software included with the EDI-OCT instrument determines the choroid thickness of the affected eye and healthy eye by recessing the macular center from the outside of the highly reflective RPE line to the visible inner scleral surface. Results The thickness of choroid in patients with monocular CSC was (443.36 ± 73.54) μm and (392.67 ± 87.82) μm, respectively. The difference between the two groups was statistically significant (P <0.05). Conclusions The choroid thickness in patients with CSC is significantly higher than that of healthy eyes, and has a better understanding of the pathogenesis of CSC, which may be helpful in clinical diagnosis and treatment. At the same time, EDI-OCT inspection technique is an important method to observe choroidal thickness.