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对福建省1994~1996年急性弛缓性麻痹(AFP)监测系统送检的257例粪便标本进行病毒分离,共检出脊髓灰质炎(脊灰)病毒(PV)21株,其中4株为I型野毒株。3年PV分离阳性率分别为19.6%、4.9%、6.4%;分离到非脊灰肠道病毒(NPEV)24株,阳性率分别为0、5.9%、16.5%。结果表明,福建省PV季节高峰已消除,野病毒已连续2年未分离到,而NPEV分离率逐年在提高。AFP病例的病原型别也从以往的I型野病毒为主转为以NPEV和疫苗株为主。其中Ⅱ型疫苗株检出率明显上升。此外,还揭示了福建省5岁以下婴幼儿PV携带率最高,NPEV感染仍以夏秋季为主。
A total of 257 stool specimens were collected from Fujian Province in the acute flaccid paralysis (AFP) monitoring system from 1994 to 1996. 21 poliomyelitis (PV) strains were detected, of which 4 were type I Wild strains. The positive rates of PV isolation in 3 years were 19.6%, 4.9% and 6.4%, respectively. 24 strains of non-polio enterovirus (NPEV) were isolated, the positive rates were 0,5.9% and 16 respectively. 5%. The results showed that the PV season peak in Fujian Province had been eliminated. The wild virus had not been separated for two consecutive years, while the NPEV isolation rate was increasing year by year. The pathogenic type of AFP cases also changed from the previous type I wild-type virus to NPEV and vaccine strains. Among them, the detection rate of type Ⅱ vaccine strains increased significantly. In addition, it also revealed that infants under 5 years of age in Fujian province have the highest PV carrying rate, while NPEV infection is still mainly based on summer and autumn.