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自1984年作者报道通过活检证实的喉癌366例,其中喉原位癌12例,原位癌伴显微浸润9例。全部患者均用手术显微镜在内窥镜下行激光声带粘膜切除术,同时亦将肿瘤周围及深层不正常组织予以气化,由于气化的深度常较表浅,因而能保留声带的正常结构。在21例经激光治疗的患者中,大多数仅经一次治疗喉部即无肿瘤复发,但也有5例治疗后复现不正常组织。其中1例又作过一次治疗,其余4例作过2～6次治疗。经6个月至4年的随诊,全部患者均无肿瘤复发。喉原位癌传统的治疗选择包括活检后全程放疗,部分或全喉切除术。作者经验认为对于
Since 1984, the authors reported 366 cases of laryngeal carcinoma confirmed by biopsy, including 12 cases of laryngeal carcinoma in situ and 9 cases of carcinoma in situ with microscopic infiltration. All patients underwent laser vocal cord mucosal resection under an endoscope with a surgical microscope, and also gasified around the tumor and deep abnormal tissue. Since the depth of gasification is often superficial, it can retain the normal structure of the vocal cords. Of the 21 laser-treated patients, most did not have a tumor recurrence after only one treatment of the throat, but there were also 5 cases of recurrence of abnormal tissue after treatment. One case was treated once again, and the remaining 4 cases were treated 2 to 6 times. After 6 months to 4 years of follow-up, all patients had no tumor recurrence. Traditional treatment options for laryngeal carcinoma in situ include full radiotherapy after biopsy and partial or total laryngectomy. The author’s experience considers that