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目的观察奥美拉唑和常规药物治疗内科消化疾病疗效对比研究及药学分析。方法选取医院内科收治的消化性疾病患者150例,随机分为观察组和对照组,每组75例。对照组采用常规药物治疗,观察组采用奥美拉唑治疗。观察2组患者临床治疗效果、幽门螺旋杆菌根除率及不良反应发生情况。结果观察组总有效率是为92.0%,高于对照组的76.0%(P<0.05);观察组幽门螺杆菌根除率为85.3%,显著高于对照组的44.0%(P<0.01);观察组不良反应发生率为4.0%,显著低于对照组的17.3%(P<0.01)。结论与一些常规的药物相比,采用奥美拉唑治疗内科消化性疾病的疗效更为显著,且不良反应发生率小,值得临床推广应用。
Objective To observe the efficacy of omeprazole and conventional drugs in the treatment of digestive diseases and pharmacological analysis. Methods 150 patients with digestive diseases admitted to hospital were randomly divided into observation group and control group with 75 cases in each group. The control group was treated with conventional drugs, while the observation group was treated with omeprazole. The clinical efficacy, eradication rate of Helicobacter pylori and the incidence of adverse reactions in the two groups were observed. Results The total effective rate in the observation group was 92.0%, which was significantly higher than that in the control group (76.0%, P <0.05). The H. pylori eradication rate in the observation group was 85.3%, which was significantly higher than that in the control group (44.0%, P <0.01) The incidence of adverse reactions in the group was 4.0%, significantly lower than that in the control group (17.3%, P <0.01). Conclusion Compared with some conventional drugs, the use of omeprazole in the treatment of medical digestive diseases is more obvious, and the incidence of adverse reactions is small, worthy of clinical application.