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目的观察复方丹参注射液联合硫酸镁治疗轻度子痫前期对患者血清C反应蛋白(CRP)及可溶性凝集素样氧化型低密度脂蛋白受体-1(Slox-1)水平的影响。方法将212例轻度子痫前期患者随机分均为观察组和对照组各106例,对照组单纯使用硫酸镁治疗,观察组使用复方丹参注射液联合硫酸镁治疗,分别于2组治疗前后检测患者血清CRP及Slox-1水平。结果治疗后2组患者血清CRP及Slox-1水平均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。结论复方丹参注射液联合硫酸镁治疗轻度子痫前期较单纯使用硫酸镁治疗能更有效地降低患者血清CRP及Slox-1水平。
Objective To observe the effects of Fufang Danshen injection and magnesium sulfate on the levels of serum C-reactive protein (CRP) and soluble agglutinin-like oxidized low density lipoprotein receptor-1 (Slox-1) in patients with mild preeclampsia. Methods A total of 212 patients with mild preeclampsia were randomly divided into observation group and control group, 106 cases in each group. The control group was treated with magnesium sulfate alone. The observation group was treated with compound Danshen injection combined with magnesium sulfate. The patients in the observation group were detected before and after treatment Patients with serum CRP and Slox-1 levels. Results Serum levels of CRP and Slox-1 in two groups after treatment were lower than those before treatment, and the difference between the two groups was statistically significant (P <0.05). Conclusion Compound Danshen injection combined with magnesium sulfate in patients with mild preeclampsia than the simple use of magnesium sulfate treatment can be more effective in reducing serum CRP and Slox-1 levels.