论文部分内容阅读
目的 :观察巴曲抗栓酶治疗突发性耳聋的疗效和对脑干听觉诱发电位 (BAEP)的影响。方法 :2 8例病人为 (男性 17例 ,女性 11例 ,年龄 4 0 .2± 1.3a)随机均分为 2组 ,治疗组用巴曲抗栓酶隔日静脉滴注 (静滴 ) ,首次 5～ 10BU ,以后每次 5BU ;对照组用右旋糖酐_4 0 2 50mLqd ,2组均加用地塞米松静滴 ,d 1为 2 0mg ,每 3d递减 5mg ,共 2wk。结果 :治疗组与对照组治愈率分别为 56%和 19% (P<0 .0 5) ,有效率分别为 78%和 62 % (P >0 .0 5) ,治疗后 1wk听力分别为 4 3± 9dB和 55± 11dB(P <0 .0 5) ;BAEP恢复与对照组无差异 (P >0 .0 5)。结论 :巴曲抗栓酶治疗突发性耳聋见效快 ,安全性好
Objective: To observe the curative effect of batroxobin on sudden deafness and the effect on brainstem auditory evoked potential (BAEP). Methods: Twenty-eight patients (17 males, 11 females, age 402 ± 1.3a) were randomly divided into two groups. The patients in the treatment group were treated with intravenous infusion of batroxobin for one day 5 ~ 10BU, each subsequent 5BU; control group with dextran _4 0 2 50mLqd, 2 groups were treated with dexamethasone intravenous infusion, d1 was 20mg, decreased by 5mg every 3d, a total of 2wk. Results: The cure rates of the treatment group and the control group were 56% and 19% (P <0.05), the effective rates were 78% and 62% respectively (P> 0.05), and the hearing rates at 1 week after treatment were 4 3 ± 9dB and 55 ± 11dB (P <0.05). There was no difference between BAEP recovery and control group (P> 0.05). Conclusion: Batroxobin is effective and safe in treating sudden deafness