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我院一例14岁儿童服用麦迪霉素二天共1.6克,引起消化道出血,现报道如下。患童男,14岁。发热咽痛一天,T38.7℃,咽部轻度充血,扁桃体不肿大。诊断上感。给口服柴胡注射液3支,一天二次,共服一天;麦迪霉素0.2克,一天四次。二天后上腹部不适,恶心无呕吐,纳差、腹泻,每日3～4次。口服胃复安后恶心消失而腹泻如前,为柏油便,上腹有压痛,大便潜血(+++)。考虑为麦迪霉素引起的消化道出血,立即停药,控制饮食,补液,使用甲氰咪胍、止血敏等,三天后出血停止,大便潜血(-),自觉症状消失痊愈。首次服用麦迪霉素,服后即有消化道症
A 14-year-old child in our hospital taking midecamycin for two days a total of 1.6 grams, causing gastrointestinal bleeding, are reported below. Male child suffering, 14 years old. Sick throat day, T38.7 ℃, pharyngeal mild congestion, tonsil does not enlarge. Diagnosis of the flu. To oral Bupleurum injection 3, twice a day for a total of one day; midecamycin 0.2 grams, four times a day. Two days after the upper abdomen discomfort, nausea and vomiting, anorexia, diarrhea, 3 to 4 times daily. Oral metoclopramide nausea disappeared and diarrhea as before, asphalt, abdominal tenderness, fecal occult blood (+++). Consider the gastrointestinal bleeding caused by midecamycin, immediate withdrawal, diet control, rehydration, use of cimetidine, hemostatic, etc., stop bleeding after three days, fecal occult blood (-), symptoms disappear and heal. Midecamycin for the first time, after serving that gastrointestinal disease