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原发性高血压４１例，其中２１例（男性１２例，女性９例：年龄５４±ｓ８ａ）采用西拉普利平均每天口服３６±１３ｍｇ，共４ｗｋ。另２０例（男性６例，女性１４例；年龄５４±７ａ）采用依那普利平均每天口服１１±３ｍｇ，共４ｗｋ。结果：２组均于治疗１Ｗｋ即开始有显著降压作用，随疗程增加，疗效日益显著（Ｐ＜０．０１）。下降幅度２组组间相似（Ｐ＞０．０５）。西拉普利尚有对体重及血清钠、氯减低的作用，且无明显不良反应。
41 cases of essential hypertension, of which 21 cases (12 males, 9 females: age 54 ± s8a) with cilazapril daily oral administration of 36 ± 13mg, a total of 4wk. The other 20 patients (6 males and 14 females; age 54 ± 7a) received enalapril an average of 11 ± 3 mg orally daily for 4 weeks. Results: Both groups began to have a significant antihypertensive effect at 1Wk. With the course of treatment increasing, the curative effect became more and more obvious (P <0.01). The decrease was similar between the two groups (P> 0.05). Cilazapril still has the effect of reducing body weight and serum sodium and chlorine, and no obvious adverse reactions.