In a previous issue of the World Journal of Gastroen-terology, we have read the article by Li et al with great interest. We would like to thank the authors for their comprehensive contribution. However, it is our wish to make minor criticism over the present study from the perspective of methodology. In a previous issue of the World Journal of Gastroen-terology, we have read the article by Li et al with great interest. We would like to thank the authors for their comprehensive contribution. However, it is our wish to make minor criticism over the present study from the perspective of methodology