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家族性结肠腺瘤病患者中腺瘤及非新生物的息肉在胃十二指肠,甚至空肠与回肠的发生率远较以往所了解者为高。本文报导在34例芬兰家族性结肠腺瘤患者中搜寻上消化道息肉的结果。方法:男女各17例,年令16～67岁(平均33岁)。4例无家族史。22例作胃十二指肠镜检查1次,11例作2～5次。有息肉样损害的患者均作内窥镜摄片,并作多处活检。19例末端回肠检查及活检系在手术时或低位回直肠吻合后经直肠镜施行,1例系尸检标本,7例作术中胆道造影,3例作总胆管探查。标本均送组织学检查。结果:肉眼所见,14个家族中发现21例胃息肉,呈多发性,常覆盖整个胃体与胃底。胃窦部息肉较少
In patients with familial colon adenomatosis, the incidence of adenomas and non-new biological polyps in the gastroduodenal, and even the jejunum and ileum is higher than previously known. This article reports the results of a search for upper gastrointestinal polyps in 34 Finnish patients with familial colon adenomas. Methods: 17 males and females, aged 16 to 67 years (average 33 years). 4 cases had no family history. Twenty-two patients had gastroduodenal examination 1 time, and 11 cases had 2 to 5 times. Patients with polypoid lesions undergo endoscopic radiographs and perform multiple biopsies. Nineteen terminal ileal examinations and biopsies were performed with a proctoscope at the time of surgery or a low back rectal anastomosis. One case was an autopsy specimen, seven cases were performed intraoperative cholangiography, and three cases were used for exploration of the common bile duct. Specimens were sent for histological examination. RESULTS: As seen by the naked eye, 21 cases of gastric polyps were found in 14 families and they were multiple, often covering the entire body of the stomach and the fundus. Gastric polyps less