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结构式药效分类袢利尿药开发单位三和化学研究所(日) 上市单位三和化学研究所1985年药理本品有抑制盐类再吸收的作用。一般利尿剂均具有相应降压作用,但本品用高血压模型实验中在呈利尿作用剂量下仅具较弱的降压作用。本品与速尿相比有较强的抗ADH作用(ADH:抵抗糖尿激素)。给与健康人一次40mg在3.5时达最高血浓度;一次80mg在4时达最高血浓度。对于各种浮肿性疾患以速尿为对照药在日本多数单位进行试验,证明本品有较高的
Structural Pharmacodynamic Categories 袢 Diuretic Development Unit Sanwa Institute of Chemistry (Japan) Listed Company Sanwa Institute of Chemistry 1985 Pharmacology This product has the effect of inhibiting salt reabsorption. Diuretics generally have the corresponding antihypertensive effect, but this product is used in hypertensive model experiments in the diuretic dose only a weak antihypertensive effect. This product is compared with furosemide has a strong anti-ADH effect (ADH: anti-diabetic hormone). Give a healthy person a 40mg 3.5 at the highest blood concentration; a 80mg reached the highest blood concentration at 4:00. For a variety of edema disease with furosemide as a reference drug in Japan most units to test that this product has a higher