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目的观察奥扎格雷钠治疗急性脑梗死的临床效果和安全性。方法选择本院47例急性脑梗死患者,除给予脑梗死常规治疗外,加用奥扎格雷钠80mg/d,连续治疗14d。治疗前后评价神经功能缺损程度和血小板凝集率、凝血酶原时间及纤维蛋白原变化。结果基本治愈6例(12.8%),显著进步23例(48.9%),进步14例(29.8%)无效4例(8.5%),临床总有效率89.2%,凝血功能的实验室指标显著改善(P<0.05)。结论奥扎格雷钠治疗急性脑梗死安全有效。
Objective To observe the clinical effect and safety of ozagrel sodium in the treatment of acute cerebral infarction. Methods A total of 47 patients with acute cerebral infarction were enrolled in this study. Ozone was given 80 mg / d in addition to conventional treatment of cerebral infarction for 14 days. Before and after treatment evaluation of neurological deficit and platelet aggregation rate, prothrombin time and fibrinogen changes. The results were basically cured in 6 cases (12.8%), significant improvement in 23 cases (48.9%), improved in 14 cases (29.8%) ineffective in 4 cases (8.5%), clinical total efficiency of 89.2%, coagulation function laboratory indicators significantly improved P <0.05). Conclusion Ozagrel sodium is safe and effective in the treatment of acute cerebral infarction.