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观察了10名功能性消化不良(FD)病人及10名健康人(HS)餐前和餐后4小时的体表胃电频谱变化。结果显示,餐后两组的AP、FZ、FC和FP的峰值均显著增加(P<0.05),两组间差异不显著。FD组FZ(<2.4,>3.8cpm)总发生率10.1％,高于HS组(4.3％,p<0.01),FP也高于HS组(16％和10.8％,P<0.05)。FD组服西沙必利5mg,3/d,7日后FP的异常节律降至11.1％,接近HS组(P>0.05),症状计分和胃排空功能均改善。提示FD组的胃排空延迟和消化不良症状可能与胃电节律紊乱增多有关。西沙必利降低胃电异常节律,FD病人可能存在肌间运动神经元功能紊乱。
Ten patients with functional dyspepsia (FD) and ten healthy subjects (HS) were observed for changes in body surface electrical spectrum before and after meals. The results showed that the peak values of AP, FZ, FC and FP in both groups increased significantly after meal (P <0.05), with no significant difference between the two groups. The overall incidence of FZ (<2.4,> 3.8 cpm) in the FD group was 10.1%, higher than that in the HS group (4.3%, p <0.01). FP was also higher in the F group than in the HS group (16% vs 10.8%, P <0.05). FD group received cisapride 5mg, 3 / d, 7 days after the FP abnormal rhythm dropped to 11.1%, close to the HS group (P> 0.05), symptom scores and gastric emptying were improved. Tip FD group of gastric emptying delay and dyspeptic symptoms may be related to the increase of gastric electrical rhythm disorders. Cisapride reduced gastric abnormality rhythm, FD patients may have dysfunction of motor neurons.