对低浓度苯接触工人健康状况的调查

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为了弄清低浓度苯环境下作业人群的健康状况,对某大型石油化工企业产生低浓度苯的5个车间采集323个样品分析。浓度范围在0.05~29.25mg/m3,其中制苯车间浓度最高,均值为4.57±6.16mg/m3;从5个车间筛选密切苯接触人群437人,选择非苯接触人群(对照组)150人,进行了外周血白细胞和淋巴细胞微核率的测定,结果表明:①外周血白细胞数虽在正常值范围之内,但非常显著低于对照组;②经常性苯接触工人淋巴细胞微核率分布高于非苯接触组,且制苯车间观察人群的淋巴细胞微核率与对照组比较,差异有显著性;③5个车间随作业环境苯浓度的增高,白细胞数有降低趋势,淋巴细胞微核率有增加的趋势。这些均证明低浓度苯对作业人群的健康有损害,尤其要注意对人体遗传物质的损伤作用。 In order to ascertain the health status of the operating population in the low-concentration benzene environment, 323 samples were collected from 5 workshops where a large petrochemical enterprise produces low-concentration benzene. The concentration range is 0.05~29.25mg/m3, among which the concentration in the benzene production workshop is the highest with an average value of 4.57±6.16mg/m3; from the 5 workshops, 437 people are closely exposed to benzene, and the non-benzene contact population is selected ( In the control group, 150 people were tested for peripheral blood leukocyte and lymphocyte micronucleus rate. The results showed that: 1 The number of peripheral white blood cells was within the normal range, but it was significantly lower than that of the control group; 2 regular benzene exposure workers The lymphocyte micronucleus rate distribution was higher than that of the non-benzene contact group, and the lymphocyte micronucleus rate of the observation group in the benzene production workshop was significantly different from that of the control group; the benzene concentration in the workplace increased and the white blood cell count decreased in 35 workshops. In the trend, the lymphocyte micronucleus rate has an increasing trend. All these prove that the low concentration of benzene is harmful to the health of the working population, especially the damage to human genetic material.
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