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目的:探讨慢性胰腺炎(CP)病人营养风险和相关危险因素。方法:应用营养风险筛查2002(NRS 2002)回顾性筛查156例CP病人的营养风险,纳入14项可能影响CP病人营养风险的临床参数,并行单因素和多因素Logistic回归分析。结果:在156例病人中,营养风险病人的比例明显高于营养不良病人(44.9%vs25.6%,χ~2=12.64,P=0.000 4)。单因素分析显示,性别、是否合并糖尿病、内镜下或外科胰腺干预、使用胰酶替代治疗、是否合并焦虑抑郁状态、是否平素进食不充分、是否使用营养支持和<3个月以上营养支持等7项因素与营养风险发生相关(P<0.01)。多因素回归结果显示,合并焦虑抑郁状态、平素进食不充分、<3个月以上营养支持等为CP病人营养风险发生的危险因素。结论:CP病人营养风险高,需早期心理干预、鼓励恰当进食和适时的肠外或肠内营养支持治疗。
Objective: To investigate nutritional risk and related risk factors in patients with chronic pancreatitis (CP). Methods: Nutritional Risk Screening 2002 (NRS 2002) was used to retrospectively investigate the nutritional risk of 156 patients with CP. 14 clinical parameters that may affect the nutrition risk of CP patients were included in the study, and univariate and multivariate logistic regression analyzes were performed. Results: Among 156 patients, the proportion of nutrition risk patients was significantly higher than that of malnourished patients (44.9% vs 25.6%, χ ~ 2 = 12.64, P = 0.000 4). Univariate analysis showed that gender, diabetes mellitus, endoscopic or surgical pancrease interventions, use of pancreatic enzyme replacement therapy, co-morbid anxiety or depression, inadequate intake of nutrients, nutritional support, and nutritional support <3 months or more Seven factors were associated with nutritional risk (P <0.01). Multivariate regression results showed that depression with anxiety and depression, usually eating inadequate, <3 months or more nutritional support CP risk factors such as nutritional risk. Conclusion: CP patients with high nutritional risk, need early psychological intervention to encourage proper eating and timely parenteral or enteral nutrition support treatment.