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目的探讨子宫内膜癌患者保留卵巢功能的手术方案。方法选择2012年8月至2015年8月间接受手术治疗的93例子宫内膜癌患者,其中43例接受保留单侧或双侧卵巢功能的手术者纳入观察组,另50例未保留卵巢功能者纳入对照组。对比两组患者术后的近远期生存率,并进行单因素及危险因素的分析。结果两组患者术后1、3、5年的生存率比较差异均无统计学意义(P>0.05)。卵巢转移与肿瘤病理类型、病理分级、病灶大小、浸润深度、腹水细胞学、血清糖类抗原125等因素有关(P<0.05)。结论子宫内膜癌患者可以选择保留卵巢功能的术式,但应对患者进行综合评价,排除危险因素的患者可认为符合手术适应征。
Objective To investigate the surgical treatment of ovarian function in patients with endometrial cancer. METHODS: Ninety-three patients with endometrial cancer who underwent surgery between August 2012 and August 2015 were selected. Forty-three patients undergoing surgery with unilateral or bilateral ovarian function were enrolled in the observation group and the other 50 patients without retained ovarian function Those who were included in the control group. Short and long term survival rates were compared between the two groups, and univariate and risk factors were analyzed. Results There was no significant difference in the survival rates between the two groups at 1, 3 and 5 years (P> 0.05). Ovarian metastasis and tumor pathological type, pathological grading, lesion size, depth of invasion, ascites cytology, serum carbohydrate antigen 125 and other factors (P <0.05). Conclusions Patients with endometrial cancer may choose to retain ovarian function, but patients should be evaluated comprehensively. Patients who have excluded risk factors should be considered as eligible for surgery.