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以N-(2-异丙酸)-邻羟基苯甲酰腙(C10H10N2O4,H3L)、2,6-吡啶二甲酸(2,6-H2PDA)与RE(NO3)3·nH2O(RE=Pr,Eu)在室温下反应,合成了配合物1[Pr2(H2L)2(HL)2(2,6-H2PDA)(H2O)2]·2H2O和配合物2[Eu2(H2L)2(HL)2(2,6-H2PDA)-(H2O)2]·2H2O,对其进行了元素分析、红外光谱、紫外光谱等表征,测定了两种配合物的晶体结构.通过紫外吸收光谱、荧光发射光谱和稳态荧光猝灭方法及其与溴化乙锭(EB)的竞争实验研究了两种配合物与小牛胸腺DNA的作用情况.结果表明,两种配合物与小牛胸腺DNA均是以插入方式结合的.
(RE = NO 3) 3 · nH 2 O (RE = Pr, N 2 O) Eu) at room temperature to synthesize the complex 1 [Pr2 (H2L) 2 (HL) 2 (2,6-H2PDA) (H2O) 2] · 2H2O and complex 2 [Eu2 (H2L) 2 (2,6-H2PDA) - (H2O) 2] · 2H2O were synthesized and characterized by elemental analysis, IR and UV spectroscopy. The crystal structures of the two complexes were determined by UV absorption spectroscopy, fluorescence emission spectroscopy and Steady-state Fluorescence Quenching Method and Its Interaction with Ethidium Bromide (EB) The effect of the two complexes on DNA of calf thymus was studied.The results showed that the two complexes and the calf thymus DNA were inserted Way combined.