曾报道,罗汉果可抑制组胺诱发的搔鼻行为。本次探讨了罗汉果提取物及其糖苷对化合物48/80诱发的搔抓背部行为的作用。方法:实验动物为6～10周龄的雌性ICR系小鼠。罗汉果提取物及其糖苷的剂量均为300、1000mg/kg,阳性对照组给予曲尼司特(300mg/kg)。1h后从小鼠的背部给予化合物4 It has been reported that Lo Han Guo inhibits histamine-induced nasal discharge. The effect of extract of Mangosteen extract and its glycosides on the back scratching behavior induced by compound 48/80 was investigated. Methods: The experimental animals were 6-10 week old female ICR mice. The dose of Lo Han Guo extract and its glycosides were both 300 and 1000 mg/kg, while the positive control group was given tranilast (300 mg/kg). Compound 4 was given from the back of the mice 1 h later