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一、国内、外常用制剂 (一)雌激素制剂过去根据化学结构将雌激素分成两大类:一类属于天然雌激素,以雌二醇为代表;另一类属合成雌激素,以己烯雌酚为代表。近年来,对于雌激素的作用机理作了深入研究后,发现上述分类并不符合雌激素的药理性能。所以目前趋向将雌激素制剂按下述分成4类。事实上,现代的各种雌激素制剂多数是合成的,下述分类是根据药理性能划分的: 1.天然雌激素相当于卵巢所分泌的三种雌
First, the domestic and foreign commonly used preparations (a) estrogen preparations in the past according to the chemical structure of estrogen is divided into two categories: one belongs to the natural estrogen, to estradiol as the representative; the other is a synthetic estrogen, diethylstilbestrol as representative. In recent years, the mechanism of action of estrogen made in-depth study and found that the above classification does not meet the estrogen pharmacological properties. So now tend to estrogen preparations are divided into four categories as follows. In fact, the majority of modern estrogen preparations are synthetic, the following classification is based on pharmacological properties of the division: 1. Natural estrogen is equivalent to ovarian secretion of the three kinds of female