论文部分内容阅读
为了解崇文区健康人群麻疹抗体水平,对0~49岁479人进行了麻疹抗体水平监测.结果显示,抗体阳性率为75.37%(361/479),阳性率较高的人群是1岁和20~29岁,分别是98.33%和93.33%;较低的是6月龄儿童,阳性率为1.69%.各年龄组间抗体阳性率的有极显著的统计学意义(P<0.001).从抗体水平看:以低抗体(1:200)为主,占44.68%,中抗体(1:800)占23.38%,高抗体(1:3200)占了30%;抗体几何平均滴度倒数(GRT)为246.72.抗体清度水平的的高低与阳性率分布一致,仍有24.64%的人处于易感水平,主要是6月龄儿童.这部分人群中有98.31%的人抗体水平<1:200.其中<1:50的占72.89%,1:50的占25.42%.经分析比较,其它年龄组抗体比较平衡稳定.因此今后预防的重点人群是6月龄儿童,建议麻疹疫苗(MV)初免提前至6月龄,并考虑可给婚前体检女青年进行MV免疫。
To understand the level of measles antibody in healthy population in Chongwen District, measles antibody levels were monitored in 479 people aged 0-49 years. The results showed that the positive rate of antibody was 75.37% (361/479), the highest positive rate was 1 year old and 20-29 years old, which were 98.33% and 93.33% respectively; the lowest was June Age children, the positive rate was 1.69%. The positive rate of antibody among all age groups was extremely statistically significant (P <0.001). From the antibody level, low antibodies (1: 200) accounted for 44.68%, medium antibodies (1: 800) accounted for 23.38%, high antibodies (1: 3200) accounted for 30% GRT) is 246.72. Antibody level and the level of the positive rate distribution of the same, there are still 24.64% of the people at a susceptible level, mainly 6-month-old children. 98.31% of human antibodies in this part of the population <1: 200. Among them, <1:50 accounted for 72.89% and 1: 50 accounted for 25.42%. After analysis and comparison, antibodies of other age groups are relatively stable. Therefore, the key population for future prevention is 6-month-old children. It is suggested that the initial immunization of measles vaccine (MV) should be advanced to 6 months of age, and MV vaccination should be considered for young women who undergo pre-marital examination.