目的探讨脑梗死患者血纤维蛋白原(Fg)水平与颈动脉粥样硬化之间的关系。方法对60例脑梗死患者进行颈动脉超声检测及血Fg水平测定,通过对Fg浓度的分层分析Fg水平与颈动脉粥样硬化斑块稳定性的关系。结果中浓度组斑块数最多,尤其易损斑块发生率最高,与低浓度组相比有统计学意义(P<0.05)。而低、高浓度组间及中、高浓度组间易损斑块发生率无明显差异。结论作为卒中患者的重要危险因素之一,血纤维蛋白原水平与脑梗死患者颈动脉粥样硬化密切相关。 Objective To investigate the relationship between fibrinogen (Fg) and carotid atherosclerosis in patients with cerebral infarction. Methods Sixty patients with cerebral infarction were examined by carotid ultrasonography and Fg levels. The relationship between Fg level and carotid atherosclerosis plaque stability was analyzed by stratified Fg concentration. Results The concentration of plaque in the concentration group was the highest, especially the incidence of vulnerable plaque was the highest, compared with the low concentration group was statistically significant (P <0.05). There was no significant difference in the incidence of vulnerable plaque between low and high concentration groups and middle and high concentration groups. Conclusion As one of the important risk factors for stroke, the level of fibrinogen is closely related to carotid atherosclerosis in patients with cerebral infarction.