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用~(31)P核磁共振研究表明,细胞色素C能诱导由心磷脂和二棕榈酰磷脂酰胆碱组成的人工脂膜发生六角形Ⅱ相的相变。阿霉素能稳定脂膜双层排列,阻止细胞色素C诱导的多形性相变。
The ~ (31) P nuclear magnetic resonance study showed that cytochrome C induced the phase transition of hexagonal phase II in the artificial lipid membrane consisting of cardiolipin and dipalmitoylphosphatidylcholine. Doxorubicin stabilizes the lipid bilayer and prevents the cytochrome C-induced polymorphism.