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肺表面活性物质的功能是降低肺泡的表面张力,增加呼气未肺泡的表面压力。它的缺乏是发生新生儿肺透明膜病(HMD)的主要原因。对此物质的研究已经有半个多世纪的历史这些观察导致了对表面活性物质的生物学研究,并给以后HMD的临床上的替代疗法奠定了基础。
The function of pulmonary surfactant is to reduce the surface tension of the alveoli and increase the surface pressure of the non-alveolar expiratory. Its absence is the leading cause of neonatal hyaline membrane disease (HMD). The investigation of this substance has been going on for more than half a century. These observations led to the biological study of surfactant and laid the foundation for future clinical alternatives to HMD.