论文部分内容阅读
目的:观察暖脐散治疗小儿腹泻的临床疗效及药理作用。方法:临床研究共观察60例腹泻患儿,随机分为两组,治疗组30例用暖脐散敷脐,对照组30例用十香暖脐膏敷脐,比较两组疗效。实验研究观察暖脐散外敷对大黄脾虚小鼠小肠推进运动的影响;对阿托品负荷小鼠小肠推进运动的影响;对新斯的明负荷小鼠小肠推进运动的影响;对大黄脾虚小鼠小肠SOD活性的影响。结果:治疗组有效率为90.0%,对照组有效率为66.7%,两组比较有显著差异(P<0.05)。动物实验表明,暖脐散能够明显抑制大黄脾虚病理模型小鼠小肠推进率,提高SOD活性,保护细胞和组织,促使肠粘膜病理改变恢复到正常的生理状态。结论:暖脐散能够发挥扶正祛邪、抗炎止泻的效应,对多种小儿腹泻疗效较好,使用方便,无毒副作用。
Objective: To observe the clinical efficacy and pharmacological effects of warm navel powder in treating infantile diarrhea. Methods: A total of 60 children with diarrhea were observed in the clinical study. They were randomly divided into two groups. The treatment group was treated with warm umbilical cord navel, and the control group with 10 fragrant umbilical creams. The curative effect was compared between the two groups. Experimental study to observe the effects of warm umbilical powder outside the small intestine to promote the movement of rhubarb spleen mice; impact on atropine-induced small intestine propulsion; impact on Neostigmine-induced small intestine propulsion; rhubarb spleen deficiency in mice with small intestine SOD Effect of activity. Results: The effective rate was 90.0% in the treatment group and 66.7% in the control group, with significant difference between the two groups (P <0.05). Animal experiments show that warm umbilical powder can significantly inhibit the small rat model of Rhubarb and spleen promote the rate of small intestine, increase SOD activity, protect cells and tissues, and promote intestinal mucosal pathological changes returned to normal physiological state. Conclusion: The warm umbilical powder can exert the effects of strengthening, removing and eliminating evil, anti-inflammatory and anti-diarrhea. It has good curative effect on many kinds of infantile diarrhea, easy to use and non-toxic side effects.