论文部分内容阅读
目的探讨自身免疫性胰腺炎的临床病理特点。方法对2例自身免疫性胰腺炎病例进行临床资料分析和光镜、免疫组化标记观察。结果自身免疫性胰腺炎的临床表现无特异性,镜下主要为胰腺弥漫性间质纤维化,中等以上小叶间导管炎细胞浸润。免疫组化显示炎细胞主要为CD4和CD8(+)的T细胞及IgG4(+)的浆细胞。结论自身免疫性胰腺炎在我国还未引起足够重视,影像学及病理学检查是诊断的主要依据。
Objective To investigate the clinicopathological features of autoimmune pancreatitis. Methods Two cases of autoimmune pancreatitis were analyzed by clinical data and light microscope and immunohistochemical staining. Results The clinical manifestations of autoimmune pancreatitis were nonspecific. The microscopic findings were diffuse interstitial fibrosis of the pancreas and infiltration of medium and small interlobular duct cells. Immunohistochemistry showed that inflammatory cells were predominantly CD4 and CD8 (+) T cells and IgG4 (+) plasma cells. Conclusions Autoimmune pancreatitis has not been given sufficient attention in our country. Imaging and pathological examination are the main basis of diagnosis.