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目的了解浙江省衢州市衢江区健康人群麻疹抗体水平,为控制麻疹采取相应措施提供参考依据。方法采用酶联免疫吸附试验对衢江区15~45岁不同年龄组健康人群进行麻疹IgG抗体血清学检测。结果本次共检测363份血清标本,阳性率为96.69%,抗体几何平均浓度(GMC)972.91 IU/L,保护率为66.67%,年龄间抗体保护率经统计学分析,差异有统计学意义(P<0.05)。不同年份间的抗体保护率经统计学检验差异有统计学意义(P<0.05)。结论衢州市衢江区健康人群麻疹抗体处于较高水平,建议及时并扩大范围接种麻疹疫苗,提高接种率,保证较高的保护率,形成有效的免疫屏障,才能有效控制麻疹。
Objective To understand the level of measles antibody in healthy people in Qujiang District of Quzhou City, Zhejiang Province, and provide reference for controlling measles. Methods Enzyme-linked immunosorbent assay was used to detect seronegative IgG antibodies to measles IgG in healthy population aged 15-45 years in Qujiang district. Results A total of 363 serum samples were tested, the positive rate was 96.69%, the mean geometric mean antibody concentration (GMC) was 972.91 IU / L, and the protection rate was 66.67%. The antibody protection rate among the groups was statistically significant P <0.05). Antibody protection rates in different years were statistically significant (P <0.05). Conclusion The measles antibody of healthy population in Qujiang District of Quzhou City is at a high level. It is suggested that measles measles can be effectively controlled by timely and wide range measles vaccination, increasing vaccination rate, ensuring high protection rate and forming an effective immune barrier.