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目的探讨应用生长抑素治疗上消化道出血患者的临床疗效。方法将本院2010年1月~2012年12月收治的90例上消化道出血患者,随机分为观察组和对照组,每组45例,对照组给予常规用药治疗;观察组在常规用药在基础上给予生长抑素治疗。对比两组患者评价临床疗效、止血时间及不良反应发生率。结果观察组的临床显效率及总有效率明显高于对照组(P<0.05);观察组的平均止血时间明显低于对照组(P<0.05);两组不良反应发生率比较差异无统计学意义(P>0.05)。结论上消化道出血的患者在输血输液补充血容量、纠正休克的基础上应用生长抑素治疗,患者止血速度快、早期再出血发生率低、输血量减少。止血时间短,不良反应小,疗效显著,值得推广应用。
Objective To investigate the clinical efficacy of somatostatin in the treatment of patients with upper gastrointestinal bleeding. Methods From January 2010 to December 2012 in our hospital, 90 patients with upper gastrointestinal bleeding were randomly divided into observation group and control group, with 45 cases in each group. The control group was given conventional drug treatment. In the observation group, On the basis of somatostatin treatment. The two groups were compared to evaluate the clinical efficacy, bleeding time and the incidence of adverse reactions. Results The clinical effective rate and total effective rate in the observation group were significantly higher than those in the control group (P <0.05). The mean bleeding time in the observation group was significantly lower than that in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups Significance (P> 0.05). Conclusion In patients with upper gastrointestinal bleeding in the transfusion infusion of blood volume, to correct shock on the basis of the application of somatostatin treatment, patients with fast bleeding, low incidence of early rebleeding, blood transfusion decreased. Hemostatic time is short, adverse reactions, significant effect, it is worth to promote the application.