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目的 探讨围生期窒息与新生儿胆红素水平变化之间的关系。方法 对 40例窒息儿 (重度窒息、轻度窒息各 2 0例 )及同期出生的正常儿 2 0例 ,分别于生后 2 4h、72h、12 0h、抽血测定总胆红素水平并分组比较。结果 重度窒息组、轻度窒息组及正常组之间 2 4h总胆红素水平比较有显著差异 (F =97.872 ,P <0 .0 1) ,72h则差异无显著意义 (F =2 .0 79,P >0 .0 5 ) ,12 0h重度窒息组总胆红素水平下降明显 ,与另两组比较差异有显著性 (F =12 7.85 2 ,P <0 .0 1) ,轻度窒息组与正常儿组间差异无显著意义。结论 窒息程度不同 ,胆红素水平变化也不同 ;应对窒息儿胆红素水平进行早期监测和干预以免发生核黄疸
Objective To investigate the relationship between perinatal asphyxia and neonatal bilirubin levels. Methods Totally 40 patients with asphyxia (severe asphyxia and mild asphyxia) and 20 normal subjects were enrolled in this study. Total bilirubin levels were determined by blood sampling at 24 h, 72 h and 120 h after birth Compare Results There was a significant difference in total bilirubin levels at 24 h between severe asphyxia group, mild asphyxia group and normal group (F = 97.872, P <0.01), but no significant difference at 72 h (F = 2.0 79, P> 0.05). The level of total bilirubin in 120h severe asphyxia group decreased significantly compared with the other two groups (F = 12 7.85 2, P <0.01), mild asphyxia There was no significant difference between group and normal group. Conclusions The degree of asphyxia is different and the level of bilirubin is also different. Early monitoring and intervention of bilirubin level should be performed to prevent kernicterus