观察了溴甲烷急性染毒家兔后遗周围神经电生理的改变。实验组家兔溴甲烷染毒８周后，体感诱发电位表现为，刺激胫后神经引起的皮层和腰髓诱发电位主波波幅下降，皮层主波潜伏期明显长于对照组（Ｐ＜０．０１），四肢肌电图表现为时程延长，幅值升高和多相百分比增加，特别是双侧后肢出现束颤和纤颤的失神经电位及代表神经元损伤的特征性巨大电位。结果提示，急性溴甲烷中毒后对周围神经，特别对脊神经有一定的实质性损害作用。 The electrophysiological changes of perineal nerve after methyl bromide acute poisoning were observed. In the experimental group, the amplitude of somatosensory evoked potential (VEP) was lower in the stimulation of posterior tibial nerve than in the control group (P <0.01) Limb EMG showed prolonged duration, increased amplitude and increased multiphase percentage, especially denervated potentials of bundle fibrillation and fibrillation on bilateral hindlimbs and characteristic giant potentials representing neuronal damage. The results suggest that acute methyl bromide poisoning on the peripheral nerves, especially on the spinal nerve have some substantial damage.