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目的:通过鼻咽癌普查了解广西苍梧县高发区鼻咽癌流行状况,探讨可持续发展的鼻咽癌早诊早治普查模式。方法:于2007年6月～2008年12月在广西苍梧县石桥镇鼻咽癌现场进行鼻咽癌普查。在鼻咽癌现场建立人口档案;进行流行病学调查;参加普查者均进行头颈部检查及间接鼻咽镜检查,鼻咽癌EB病毒壳抗原IgA抗体(IgA/VCA)和早期抗原IgA抗体(IgA/EA)血清学检测;检查结果可疑和血清学结果阳性者均进行鼻内镜检查;鼻咽部可疑病变者行活组织病理检查;鼻咽癌普查结果均输入电脑,应用EpiData3.1建立数据库。结果:鼻咽癌现场筛查人群8458人,其中EB病毒IgA/VCA阳性522例,EB病毒IgA/EA阳性28例,进行鼻内镜检查410例,鼻咽部活组织检查45例,检出鼻咽癌12例,其中早期鼻咽癌6例,接受治疗11例。鼻咽癌人群检出率141.87/10~5,早诊率50%,治疗率91.6%。结论:广西苍梧县鼻咽癌早诊早治普查方案是鼻咽癌防治的重要策略之一,而鼻咽癌早诊早治普查工作应持续发展。
OBJECTIVE: To understand the epidemic situation of nasopharyngeal carcinoma in high incidence area of Cangwu County of Guangxi through the general survey of nasopharyngeal carcinoma, and to explore the mode of early diagnosis and treatment of nasopharyngeal carcinoma with sustainable development. Methods: From June 2007 to December 2008, a survey of nasopharyngeal carcinoma was conducted on the site of nasopharyngeal carcinoma in Shiqiao Town, Cangwu County, Guangxi Province. Epidemiological survey was conducted in all NPCs. Head and neck examination and indirect nasopharyngoscopy were performed on all the census participants. EBV-IgA / IgA antibody and early antigen IgA antibody of nasopharyngeal carcinoma (IgA / EA) serological test; examination results were suspicious and serological positive were detected by endoscopy; nasopharyngeal lesions were biopsy biopsy; nasopharyngeal cancer screening results were entered into the computer, using EpiData3.1 build database. Results: 8458 people were screened by on-site screening of nasopharyngeal carcinoma. Among them, 522 were positive for Epstein-Barr virus (IgA / VCA) and 28 were IgE / EA positive for Epstein-Barr virus (EBV), 410 for nasal endoscopy, 45 for nasopharyngeal biopsy, Pharyngeal cancer in 12 cases, of which 6 cases of early nasopharyngeal carcinoma, 11 cases of treatment. The detection rate of nasopharyngeal carcinoma was 141.87 / 10 ~ 5, the diagnosis rate was 50% and the treatment rate was 91.6%. Conclusion: The early diagnosis and treatment of nasopharyngeal carcinoma in Cangwu County of Guangxi is one of the important strategies for the prevention and treatment of nasopharyngeal carcinoma. However, the early diagnosis and treatment of nasopharyngeal carcinoma should be continued.