论文部分内容阅读
乳酸-羟基乙酸共聚物[poly(lactic-co-glycolic acid),PLGA]药物缓释系统可在靶位实现局部持久高浓度给药,降低系统药物浓度。本研究就PLGA微球的生物降解性、生物相容性、抗肿瘤药物PLGA缓释微球的制备及其在间质化疗中的实验和临床研究作一综述。
LDPE (poly (lactic-co-glycolic acid), PLGA] drug delivery system can be achieved at the target site of local sustained high concentration of drug delivery, reduce the system drug concentration. This review summarizes the biodegradability and biocompatibility of PLGA microspheres, the preparation of antitumor drug PLGA sustained-release microspheres and its experimental and clinical research in interstitial chemotherapy.