目的探讨温热水浴疗法联合液氮冷冻治疗多发性镶嵌疣的临床疗效和安全性。方法将以板蓝根、薏苡仁、夏枯草、马齿苋为基本方的中药各30g浸入2 000mL冷水中浸泡30min,武火烧开后文火煮沸20min,取药液,待降至45℃~55℃时将患处浸入药液浸泡20~30min,再用剪刀或矬子将浸渍柔软的疣体削薄,以不出血为度,医用胶布封包至次日晨,均1次/d,治疗2~4个疗程,接着将疣体刮除至根部和予冷冻疗法治疗。每个冷冻疗程的第3周开始再行温热疗法治疗7d。3个月后判定疗效。结果 58例患者中,治愈42例,好转15例,无效1例,有效率98.27%。随访至今,未见复发。结论温热水浴疗法联合液氮冷冻治疗多发性镶嵌疣的临床疗效好,患者依从性高,治疗成本低,操作简单,安全性好。 Objective To investigate the clinical efficacy and safety of warm water bath combined with liquid nitrogen freezing in the treatment of multiple invasive warts. Methods The Radix Isatidis, Coix Seed, Prunella vulgaris, purslane as the basic side of the Chinese medicine each 30g immersed in 2 000 mL cold water soak 30min, the fire was boiled after gentle heat boil 20min, take the liquid until it drops to 45 ℃ ~ 55 ℃ The affected area immersed in liquid soak for 20 ~ 30min, and then scissors or prickly heat impregnated wart body thinning, with no bleeding for the degree, medical tape wrapped to the next morning, are 1 / d, the treatment of 2 to 4 courses , Followed by scraping the wart to the roots and cryotherapy. Week 3 of each cycle of cryotherapy followed by thermotherapy for 7 days. After 3 months to determine the efficacy. Results Of the 58 patients, 42 were cured, 15 were improved, 1 was ineffective, and the effective rate was 98.27%. Follow-up so far, no recurrence. Conclusion Warm water bath combined with liquid nitrogen freezing treatment of multiple inlay warts clinical efficacy, patient compliance, low cost, simple operation, good safety.