目的:探讨影响子宫肌瘤发生的危险因素。方法:采用病例对照研究方法,对118例病例及相同例数的对照所得资料进行非条件Logistic回归分析。结果:患有慢性妇科炎症、乳腺增生、恶性肿瘤家族史及一级亲属中患有子宫肌瘤为主要的危险因素,其OR值分别为7.418、6.349、3.033、6.259。豆制品、蔬菜、水果摄入量大及累计哺乳时间长是主要的保护因素。结论:子宫肌瘤的发病是多因素综合作用的结果,包括生育因素、饮食因素、遗传等多方面。 Objective: To explore the risk factors of uterine fibroids. Methods: A case-control study was used to analyze the non-conditional logistic regression analysis of 118 cases and the same number of controls. Results: The patients with chronic gynecological inflammation, hyperplasia of mammary glands, family history of malignant tumor and first-degree relatives had the main risk factors of uterine fibroids. The OR values ​​were 7.418, 6.349, 3.033 and 6.259 respectively. Soy products, vegetables, fruits and large amounts of accumulated breast-feeding time is the main protective factor. Conclusion: The incidence of uterine fibroids is the result of multifactorial combination of factors, including fertility factors, dietary factors, genetic and other aspects.