研究了不同剂量的Ｌ精氨酸（ＬＡｒｇ）以及与谷氨酸（Ｇｌｕ）合用时对神经系统（海马区）的影响，以及ＮＯ介导谷氨酸的神经毒作用。通过观察小鼠的学习与记忆的过程，各组与正常对照组之间的被动回避反应的结果显示其嗜暗反应的潜伏期在大剂量ＬＡｒｇ与ＬＡｒｇ及Ｇｌｕ合用组明显延长，同时观察病理切片显示海马区的神经元细胞减少，神经胶质细胞增多等方面有不同程度的变化，ＮＯ作用具有浓度依赖性，大剂量有神经毒作用，从而揭示ＮＯ在影响小鼠神经系统发育及功能方面有一定作用 The effects of different doses of L-arginine (L-Arg) and glutamate (Glu) on the nervous system (hippocampus) were studied, and the neurotoxic effect of NO on glutamate was also investigated. By observing the process of learning and memory in mice, the results of passive avoidance reaction between each group and the normal control group showed that the incubation period of the phagocytic reaction was significantly prolonged in high-dose L-Arg and L-Arg and Glu combined groups, meanwhile, Observation of pathological sections showed that neurons in the hippocampus decreased, glial cells increased in varying degrees, the role of NO has a concentration-dependent, high-dose neurotoxic effect, thus revealing the role of NO in the development of the nervous system in mice and Function has a role