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肌注或腹腔注射阿魏洛芬对小鼠二甲苯耳廓炎症、大鼠角叉菜胶性足肿胀和急性胸膜炎以及巴豆油性肉芽肿均有明显抗炎作用(剂量范围在50～100mg/kg之间,并呈一定的量效关系。对小鼠醋酸扭体反应和光辐射性疼痛型亦显示较强的镇痛效应(100～300mg/kg)。其体外(艾氏腹水癌)体内(S180实体瘤)抑瘤结果表明对前者抑制率高于后者。提示该药可能成为较有希望的非甾体类抗炎抗肿瘤药物。
Intramuscular or intraperitoneal injection of ubiprofen in mice xylene auricle inflammation, rat carrageenan paw edema and acute pleurisy as well as oval granuloma have a significant anti-inflammatory effect (dose range between 50 ~ 100mg / kg , And showed a certain dose-effect relationship.The mice acetic acid writhing reaction and light radiation pain type also showed a strong analgesic effect (100 ~ 300mg / kg) in vitro (Ehrlich ascites carcinoma) in vivo (S180 solid tumor ) Inhibition of tumor results showed that the former inhibition rate higher than the latter, suggesting that the drug may become more promising non-steroidal anti-inflammatory anti-tumor drugs.