2. 您的位置
3. 首页
4. 期刊论文
5. Design and immunogenicity assessment of HIV-1 virus-like particles as a candidate vaccine

Design and immunogenicity assessment of HIV-1 virus-like particles as a candidate vaccine

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：dahar005

【摘 要】

：

The rapid growth of the global HIV/AIDS epidemic makes it a high priority to develop an effective vaccine.Since a live attenuated or inactivated HIV vaccine is

【作 者】

：

ZHANG XiZhen WANG XiaoDan ZHAO 

【机 构】

：

NationalEngineeringLaboratoryforAIDSVaccine,KeyLaboratoryforMolecularEnzymologyandEngineeringofMinis

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2011年11期

【关键词】

：

病毒样颗粒 艾滋病毒 候选疫苗 免疫原性 设计 HIV-1 评估 安全问题 HIV-1 cotransfection stable cell line viru 

【基金项目】

：

supported by the Na-tional Natural Science Foundation of China （Grant No. 30371317） to Kong Wei

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

The rapid growth of the global HIV/AIDS epidemic makes it a high priority to develop an effective vaccine.Since a live attenuated or inactivated HIV vaccine is not likely to be approved for clinical application due to safety concerns,HIV virus like partic

其他文献

Comparative study of the mechanical properties,micro-structure,and composition of the cranial and be

Woodpeckers are well able to resist head injury during repeated high speed impacts at 6-7 m s-1 with decelerations up to 1000 g.This study was designed to compa

期刊

大斑啄木鸟力学性能微结构云雀头部组成X-射线粉末衍射扫描电子显微镜woodpeckerheadmechanical propertymic

Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplan

Reduced cellular immune function in patients after liver transplantation easily results in many types of viral infections,such as Epstein-Barr virus.Epstein-Bar

期刊

多发性骨髓瘤病毒感染EPSTEIN-BARR病毒肝移植细胞免疫功能WESTERN印迹恶性肿瘤细胞骨髓瘤细胞liver transplantati

Epitope variation in the Newcastle disease virus HN gene under antibody immune selective pressure i

The influence of antibody immune selective pressure on Newcastle disease virus (NDV) HN and F gene mutations was studied in cell cultures.NDV field strain TZ060

期刊

鸡新城疫病毒细胞培养HN基因选择压力抗体抗原表位免疫基因突变Newcastle disease virus HN gene F gene

Metagenome-based analysis：A promising direction for plankton ecological studies

The plankton community plays an especially important role in the functioning of aquatic ecosystems and also in biogeochemical cycles. Since the beginning of mar

期刊

微生物生态学宏基因组基础水生生态系统浮游生物群落形态识别生态系统功能生物地球化学metagenome plankton community mo

Recent progress of sensory system research in China

<正>From human to insects, the sensory system is the part of the nervous system responsible for processing sensory information. Commonly recognized sensory syst

期刊

感觉系统中国神经系统感觉信息感觉神经元躯体感觉神经通路神经科学

Immunogenicity and virus-like particle formation of rotavirus capsid proteins produced in transgenic

The human pathogen, group A rotavirus, is the most prevalent cause of acute infantile and pediatric gastroenteritis worldwide, especially in developing countrie

期刊

转基因烟草植株轮状病毒感染病毒衣壳蛋白植物生产免疫原性基因表达水平病毒样颗粒BLOT分析rotavirus virus-like particl

Translational medicine in China

<正>Translational medicine has recently experienced an upsurge in interest and funding worldwide. Many translational research programs, centers and institutes h

期刊

医学转化中国研究机构

The dynamical contact order： Protein folding rate parameters based on quantum conformational transi

Protein folding is regarded as a quantum transition between the torsion states of a polypeptide chain.According to the quantum theory of conformational dynamics

期刊

蛋白质折叠量子跃迁构象变化动力学订购量子理论转动惯量接触特性moment of inertia dynamical contact order

Opportunity and challenge： ten years of proteomics in China

<正>Proteomics is a science that focuses on the global analysis of protein expression and function in organisms. Although it is still a relatively new field, it

期刊

蛋白质组学中国科学研究计划生命科学生物体内科学家

Survival analyses of symbionts isolated from Endocarpon pusillum Hedwig to desiccation and starvati

This work deals with the survival analyses of the symbionts isolated from the lichen E.pusillum under desiccation and starvation stress.The mycobiont of the sym

期刊

干燥应力生存分析共生菌压力饥饿扫描电子显微镜透射电子显微镜细胞密度lichens mycobiont phycobiont SEM TE