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基于临床、放射及组织学的原因,以前曾将骨肉瘤再分为11种,认识这些亚类临床表现的变异对估计临床研究的结果有重要意义。某些具有很多小细胞的骨肉瘤可能类似尤汶氏瘤,鉴别这一组骨肉瘤很重要,因为它需行手术切除而不像尤汶氏瘤那样应用放疗。作者研究Mayo医院治疗的近1000例骨生肉瘤和300例尤汶氏肉瘤,发现一组12个肿瘤,加上会诊的12例,其组织学图象既像尤汶氏肉瘤又像骨肉瘤,作者称其为小细胞骨肉瘤,强调正确诊断这一病变的重要性,并指出勿与尤汶氏肉瘤混淆。资料和发现:复习了全部肿瘤的组织切片、随访资料及17例术前X线片。全组男、女各12人,年龄9～83岁,平均28岁。长骨受侵19例,其中15例病变靠近较大管状骨之一端(股10、肱6、胫2、腓1),另有髂骨3例、颅骨肩胛骨各1例。临床症状:疼痛
Based on clinical, radiological, and histological reasons, osteosarcomas were previously subdivided into 11 types. It is important to understand the clinical manifestations of these subtypes to estimate clinical outcomes. Some osteosarcomas with many small cells may resemble Uwen’s tumor. It is important to identify this group of osteosarcomas because it requires surgical resection rather than radiotherapy like the Yewing tumor. The authors studied nearly 1,000 cases of osteosarcoma and 300 cases of U.M. sarcoma treated by Mayo Hospital and found a group of 12 tumors, together with 12 cases of consultation, whose histological images resembled that of ouvenous sarcoma and osteosarcoma. The authors called it a small cell osteosarcoma, emphasizing the importance of correct diagnosis of this lesion and pointed out that it should not be confused with UWE. Data and Findings: Review of all tumor tissue sections, follow-up data, and 17 preoperative radiographs. The group has 12 men and 12 women, aged from 9 to 83 years, with an average age of 28 years. There were 19 cases of long bone invasion, of which 15 cases were near one end of the larger tubular bone (female 10, iliac 6, iliac 2, and iliac 1), and 3 cases of tibia and 1 of skull scapula. Clinical symptoms: pain