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目的应用磁共振张量成像(DTI)研究急性后循环脑梗塞中FA值的变化规律,为临床提供诊断依据。方法选择发病3 d内的急性后循环梗塞患者68例,根据发病时间分为超急性期组(<6 h)及急性期组(6 h~3 d),分别测量不同时期梗死区和健侧区的FAAV值,使用配对t检验分析不同时期梗死侧与梗死对侧有无差异。结果超急性期19例PCCI患者梗死区FA值梗死区FA值平均值(0.439±0.105),梗死对侧FA值平均值(0.339±0.098),两侧比较有统计学差异(t=9.478,P<0.001);急性期组患者共49例,梗死区FA值平均值(0.275±0.14),梗死对侧FA值平均值(0.467±0.145),两侧比较有统计学差异(t=11.254,P<0.001)。结论定量分析DTI的FA值可以协助早期诊断脑梗死,并帮助精确临床分期。
Objective To study the change rule of FA in acute posterior circulation cerebral infarction by using magnetic resonance tensor imaging (DTI) to provide the basis for clinical diagnosis. Methods Sixty-eight patients with acute posterior circulation infarction within 3 days after onset were divided into two groups: hyperacute group (<6 h) and acute phase (6 h-3 d) according to the time of onset. The infarct size and contralateral District FAAV value, paired t-test analysis of different stages of infarction and contralateral contralateral differences. Results The average value of FA in the infarction area (0.439 ± 0.105) and the contralateral FA value (0.339 ± 0.098) in infarction area in 19 patients with hyperacute stage PCCI were statistically significant (t = 9.478, P <0.001). There were 49 patients in the acute phase group, the average value of FA in infarction area was (0.275 ± 0.14), the average value of contralateral FA in infarction area (0.467 ± 0.145), there was significant difference between the two sides (t = 11.254, P <0.001). Conclusions Quantitative analysis of FA values in DTI can assist in early diagnosis of cerebral infarction and help in accurate clinical staging.