AIM To evaluate how different levels of adherence to a mediterranean diet(MD) correlate with the onset of functional gastrointestinal disorders.METHODS As many as 1134 subjects(598 M and 536 F;age range 17-83 years) were prospectively investigated in relation to their dietary habits and the presence of functional gastrointestinal symptoms.Patients with relevant chronic organic disease were excluded from the study.The Mediterranean Diet Quality index for children and adolescents(KIDMED) and the Short Mediterranean Diet Questionnaire were administered.All subjects were grouped into five categories according to their ages:14-24 years;25-34;35-49;50-64;above 64.RESULTS On the basis of the Rome Ⅲ criteria,our population consisted of 719(63.4%) individuals who did not meet the criteria for any functional disorder and were classified as controls(CNT),172(13.3%) patients meetingcriteria for prevalent irritable bowel syndrome(IBS),and 243(23.3%) meeting criteria for prevalent functional dyspepsia(FD).A significantly lower adherence score in IBS(0.57 ± 0.23,P < 0.001) and FD(0.56 ± 0.24,P < 0.05) was found compared to CNT(0.62 ± 0.21).Females with FD and IBS exhibited significantly lower adherence scores(respectively 0.58 ± 0.24,P < 0.05 and 0.56 ± 0.22,P < 0.05) whereas males were significantly lower only for FD(0.53 ± 0.25,P < 0.05).Age cluster analyses showed a significantly lower score in the 17-24 years and 25-34 year categories for FD(17-24 years:0.44 ± 0.21,P < 0.001;25-34 years:0.48 ± 0.22,P < 0.05) and IBS(17-24 years:0.45 ± 0.20,P < 0.05;24-34 years:0.44 ± 0.21,P < 0.001) compared to CNT(17-24 years:0.56 ± 0.21;25-34 years:0.69 ± 0.20).CONCLUSION Low adherence to MD may trigger functional gastrointestinal symptoms,mainly in younger subjects.Moreover,with increasing age,patients tend to adopt dietary regimens closer to MD. AIM To evaluate how different levels of adherence to a mediterranean diet (MD) correlate with the onset of functional gastrointestinal disorders. METHODS As many as 1134 subjects (598 M and 536 F; age range 17-83 years) were prospectively investigated in relation to to their dietary habits and the presence of functional gastrointestinal symptoms. Patients with relevant chronic organic disease were excluded from the study. Mediterranean Diet Quality index for children and adolescents (KIDMED) and the Short Mediterranean Diet Questionnaire were administered. All subjects were grouped into five above 64.RESULTS On the basis of the Rome III criteria, our population consisted of 719 (63.4%) individuals who did not meet the criteria for any functional disorder and were classified as controls (CNT), 172 (13.3%) patients meeting criteria for prevalent irritable bowel syndrome (IBS), and 243 (23.3%) meeting criteria for prevalent functional dyspe (1.07 ± 0.23, P <0.001) and FD (0.56 ± 0.24, P <0.05) were found compared to CNT (0.62 ± 0.21) .Females with FD and IBs significantly The results showed that the lower males were significantly lower for only FD (0.53 ± 0.25, P <0.05) .Age cluster analyzes showed a significantly lower score in the 17 (P <0.05 and 0.56 ± 0.22, P < -24 years and 25-34 year categories for FD (17-24 years: 0.44 ± 0.21, P <0.001; 25-34 years: 0.48 ± 0.22, P <0.05) (17-24 years: 0.56 ± 0.21; 25-34 years: 0.69 ± 0.20) .CONCLUSION Low adherence to MD may trigger functional gastrointestinal symptoms (P <0.05; 24-34 years: 0.44 ± 0.21, , mainly in younger subjects. More over, with increasing age, patients tend to adopt dietary regimens closer to MD.