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目的:应用洛赛克治疗脑出血并发应激性溃疡上消化出血。方法:用洛赛克治疗64例脑出血并发应激性溃疡上消化道出血,用西米替丁治疗50例作为对照组,用胃管抽了胃液监测临床效果。结果:洛赛克组,总有效率93.8％,西米替丁组,总有效率38.0％,两组比较差异有非常显著性(P<0.01)。结论:洛赛克是一种新型的胃酸泵抑制剂,它可以抑制胃酸分泌的最后步骤,使胃酸分泌减少,使胃酸pH值上升。能有效地治疗应激性溃疡上消化道出血。
Objective: Losec treatment of cerebral hemorrhage complicated by stress ulcer on upper gastrointestinal bleeding. Methods: Losec treated 64 cases of cerebral hemorrhage with stress ulcer and upper gastrointestinal bleeding, and 50 cases of cimetidine were used as control group. Gastric tube was used to monitor the clinical effect. Results: In the Losec group, the total effective rate was 93.8%. The total effective rate was 38.0% in the cimetidine group. There was a significant difference between the two groups (P <0.01). Conclusion: Losec is a new type of gastric acid pump inhibitor, which can inhibit the final step of gastric acid secretion, so that gastric acid secretion decreased, so that gastric pH increased. Can effectively treat stress ulcer upper gastrointestinal bleeding.