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目的通过对有关糖尿病危险因素的病例对照研究结果进行Meta分析,综合评价居民2型糖尿病常见危险因素,为预防与控制糖尿病提供依据,从而降低糖尿病的发病率与致残率。方法应用Meta分析方法对国内10篇有关居民2型糖尿病危险因素的病例对照研究进行定量综合分析。统计处理采用Meta分析的固定效应模型和随机效应模型。运用Review Manager5.0进行一致性检验及合并比值比(OR值)和95%置信区间的计算。结果肥胖、高脂饮食、高血压、吸烟、饮酒等因素的合并OR值和95%置信区间分别为1.61(1.23,2.12)、2.53(1.16,5.52)、1.85(1.32,2.59)、2.06(1.45,2.93)、1.57(1.34,1.84)。结论肥胖、高脂饮食、高血压、吸烟、饮酒等与居民2型糖尿病的发生有关。
Objective To analyze the risk factors associated with diabetes mellitus by meta-analysis of the results of a case-control study to evaluate the common risk factors of type 2 diabetes in residents and provide a basis for the prevention and control of diabetes mellitus, thereby reducing the incidence of diabetes and morbidity. Methods A meta-analysis of 10 case-control studies on risk factors of type 2 diabetes among residents in China was conducted by Meta-analysis. Statistical analysis using the fixed effect model Meta analysis and random effects model. Use Review Manager5.0 consistency test and the merger odds ratio (OR value) and 95% confidence interval calculation. Results The combined odds ratio (OR) and 95% confidence intervals of obesity, high fat diet, hypertension, smoking and drinking were 1.61 (1.23,2.12), 2.53 (1.16,5.52), 1.85 (1.32,2.59), 2.06 , 2.93), 1.57 (1.34, 1.84). Conclusion Obesity, high fat diet, high blood pressure, smoking, drinking and other related to the occurrence of type 2 diabetes in residents.