肉碱对于长链脂肪酸代谢和能量的产生非常重要，但有关肉碱在中枢神经系统（ＣＮＳ）的作用则知之甚少。最近有人证明肉碱可防止脑缺血并改善Ａｌｚｈｅｉｍｅｒ病人的认知功能。该文对儿科人群脑脊液（ＣＳＦ）、血与尿中肉碱进行测定，并调查病理性ＣＮＳ疾病对其的影响。方 Carnitine is important for long chain fatty acid metabolism and energy production, but little is known about the role of carnitine in the central nervous system (CNS). Recently, it has been demonstrated that carnitine prevents cerebral ischemia and improves cognitive function in Alzheimer’s patients. This article measured cerebrospinal fluid (CSF), blood and urine carnitine in pediatric population, and investigated the impact of pathological CNS disease on it. square