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5. Promoter hypermethylation of death-associated protein kinase gene in cholangiocarcinoma

Promoter hypermethylation of death-associated protein kinase gene in cholangiocarcinoma

来源 :国际肝胆胰疾病杂志：英文版 | 被引量 : 0次 | 上传用户：eagleqizha

【摘 要】

：

BACKGROUND:Death-associated protein kinase(DAPK) is a Ca2+/calmodulin-regulated Ser/Thr kinase which is involved in apoptosis. The aberrant methylation of its p

【作 者】

：

Liu  Xiao-Fang Kong  Fan-Min X 

【机 构】

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QingdaoUniv,ChinaMedUniv

【出 处】

：

国际肝胆胰疾病杂志：英文版

【发表日期】

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2007年4期

【关键词】

：

CHOLANGIOCARCINOMA DAPK GENE methylation-specific PCR EPIGENETIC ALTERATION chol 

【基金项目】

：

The study was supported by a grant from the Provincial Outstanding Youth Foundation of Shandong, China (No. 2005BS02008).

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BACKGROUND:Death-associated protein kinase(DAPK) is a Ca2+/calmodulin-regulated Ser/Thr kinase which is involved in apoptosis. The aberrant methylation of its promoter region CpG islands may be one of the important mechanisms of carcinogenesis. We studied

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