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目的研究分析雌激素联合抗生素治疗萎缩性阴道炎的临床效果。方法对116例萎缩性阴道炎患者进行随机对照分组,分为治疗组和对照组;治疗组58例用尼尔雌醇口服加欧维婷乳膏和甲硝唑栓阴道内给药;对照组58例仅用欧维婷乳膏和甲硝唑栓阴道内给药;连续用药1周为1个疗程,停药1周后观察疗效,3个月后复诊再次判定疗效。结果治疗组和对照组1个疗程(7 d)有效率均为100%,停药3个月后复诊治疗组无复发,对照组复发率为13.8%,两组比较差异有统计学意义。结论雌激素联合抗生素阴道内给药可有效治疗萎缩性阴道炎,加用尼尔雌醇全身用药可降低复发率。
Objective To study the clinical effect of estrogen combined with antibiotics in the treatment of atrophic vaginitis. Methods One hundred and sixty-six patients with atrophic vaginitis were randomly divided into treatment group and control group. In the treatment group, 58 patients were treated with nylostanol orally and Ouwei Ting cream and metronidazole suppository intravaginally. In the control group, 58 patients Only Ouwei Ting cream and metronidazole suppositories intravaginal administration; continuous treatment for 1 week for a course of treatment, withdrawal observed after 1 week, 3 months after the referral to determine the effect again. Results The effective rate was 100% for one course of treatment (7 days) in treatment group and control group, and no recurrence in treatment group after three months withdrawal, the recurrence rate in control group was 13.8%. There was significant difference between the two groups. Conclusion Intravaginal administration of estrogen combined with antibiotics can effectively treat atrophic vaginitis, and systemic administration of nylestriol can reduce the recurrence rate.