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目的分析类固醇性结核病的临床特点。方法回顾性分析2001—2006年间在类固醇激素治疗过程中发现的59例住院结核病例。结果59例均经过12个月的抗结核治疗,有效率78.3%,5例死亡患者均为耐多药结核病(MDR-TB),无缓解者8例;胸部X线表现病变广泛,病变缩小49例,空洞缩小12例;痰结核分枝杆菌菌阴转17例。结论类固醇性结核病重在预防,需定期随访X线胸片和痰抗酸染色镜检,及时治疗可以获得满意疗效。
Objective To analyze the clinical features of steroid-resistant tuberculosis. Methods A retrospective analysis of 59 cases of hospitalized tuberculosis found during steroid treatment between 2001 and 2006 was conducted. Results All of the 59 patients were treated with anti-TB therapy for 12 months, with an effective rate of 78.3%. All 5 patients died of MDR-TB and 8 had no remission. The X-ray findings of chest showed extensive lesions and the lesions were reduced by 49 Cases, empty narrowed in 12 cases; sputum Mycobacterium tuberculosis negative in 17 cases. Conclusion Steroid-induced tuberculosis is important in the prevention. Regular follow-up of X-ray and sputum acid-fast staining for microscopic examination can provide satisfactory results.