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采用 2 4小时动态心电图测定 50例Ⅱ型糖尿病患者心率变异指数和心率 ,并与 50例年龄、性别配对的正常人比较。结果 :Ⅱ型DM患者心率变异指数比正常人明显减低 (P <0 0 1 ) ,且 2 4小时平均心率和最慢心率比正常人增快 (P <0 0 1 )。其中 1 7例合并缺血性心脏病患者心率变异指数更减低 (P <0 0 5)。DM患者交感神经张力升高 ,迷走神经张力减低 ,伴有缺血性心脏病患者更显著 ,这可能意味着患者日后发生心性猝死的危险增加。
The 24-hour ambulatory electrocardiogram was used to measure the heart rate variability and heart rate in 50 patients with type 2 diabetes mellitus, and compared with 50 age and sex matched normal subjects. Results: The heart rate variability index was significantly lower in patients with type Ⅱ DM than in normal people (P <0.01), and the average heart rate and heart rate at 24 hours were faster than those in normal people (P <0.01). Seventeen patients with ischemic heart disease had a lower heart rate variability index (P <0.05). Increased sympathetic tone and decreased vagal tone in patients with DM, more pronounced in those with ischemic heart disease, may indicate an increased risk of sudden cardiac death in the future.