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目的认识轻度胃肠炎伴良性婴幼儿惊厥(BICE)的临床特点,做到正确诊断和合理治疗。方法对年龄在3～36个月的轻度胃肠炎伴惊厥的患儿进行临床观察和出院后18个月以上的随访。结果12例诊断为BICE,发病年龄(16.0±6.5)个月,6例(50%)冬季发病,9例(75%)3d内发生惊厥,为全身性或部分性发作,7例(58%)有早期频繁发作,一次病程中惊厥平均发作2.1次。发作间期EEG、脑影像学、血生化及脑脊液检查正常。惊厥停止后未行抗痫治疗,3例(25%)复发,复发≤2次,病程最长为8个月。所有病例精神运动发育正常。结论本组BICE具有以下特点:1～2岁高发,冬季多发,无家族史;无热惊厥多出现于病程的早期,全身性或部分性发作,早期频繁发作多见;血电解质、血生化、脑脊液、脑影像学和发作间期脑电图正常;部分病例可复发,病程少于1年,预后好。惊厥停止后不推荐应用抗癫痫药。
Objective To understand the clinical features of mild gastroenteritis with benign infantile convulsions (BICE) and achieve the correct diagnosis and reasonable treatment. Methods The clinical observation of children with mild gastroenteritis and convulsions aged 3 to 36 months were followed up for more than 18 months after discharge. Results Twelve cases were diagnosed as BICE with onset age of (16.0 ± 6.5) months, onset of winter in 6 cases (50%) and convulsion in 9 cases (75%) of 3days, with systemic or partial seizures and 7 cases (58% There are frequent episodes of early, seizures in a course of an average of 2.1 episodes. Interictal EEG, brain imaging, blood biochemistry and cerebrospinal fluid were normal. Convulsions did not stop after anti-epilepsy treatment, 3 patients (25%) relapse, relapse ≤ 2 times, the longest duration of 8 months. All cases of normal mental development. Conclusion This group of BICE has the following characteristics: high incidence of 1 to 2 years old, multiple in winter, no family history; no febrile seizures occurred in the early course of the disease, systemic or partial seizures, frequent early episodes of frequent; blood electrolytes, blood biochemistry, Cerebrospinal fluid, brain imaging and interictal EEG normal; some cases of recurrent, duration less than 1 year, the prognosis is good. Anticonvulsants are not recommended after convulsions have stopped.